Sublingual NAD+, NMN & NR: Is It a Good Idea?

Sublingual (under the tongue) delivery is recommended for a better effectiveness of NAD+, NMN and NR molecules. 

IS SUBLINGUAL MORE BIOAVAILABLE THAN CAPSULES?

With sublingual delivery, there is more rapid absorption via the blood vessels under the tongue rather than via the digestive tract. 

https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1092.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513449/

Sublingual delivery is not filtered by the liver and can reach systemic circulation intact, resulting in greater bioavailability than capsules.

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Sublingual delivery is recommended for all NAD+ metabolites and precursors to avoid digestion in the stomach and liver.

The absorption of molecules delivered through the sublingual route can be 3 to 10 times greater than oral route and is only surpassed by direct IV injection.

https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1092.pdf

However....

NR is not acceptable for sublingual use. 

WHY NOT?

NR is not stable, it needs chloride to be stable (Elysium's Basis and TruNiagen are both NR Chloride).

NR Chloride is only available in capsule form due to its very bitter taste.

NR Chloride is metabolized to Nicotinamide when it passes through the stomach and liver, which is why it is far less effective than NMN and NAD+. 

https://dataspace.princeton.edu/jspui/bitstream/88435/dsp01js956j498/1/Liu_princeton_0181D_12390.pdf

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