NAD+ Precursors: The biology and Therapeutic Potential of NMN and NR

NAD+ precursors such as NR and NMN, have been extensively studies over the past years due to their potential benefits on humans and animals. 

Supplementing these NAD+ intermediates has shown preventive and therapeutic effects, ameliorating age-associated pathophysiologies and disease conditions.

In this study, researchers focused on the biology of NMN and NR, in an in vivo context.

Shop NAD+ & NMN here!

These NAD+ precursors are found in a wide variety of our daily foods, such as vegetables, fruits, and meat ().

Interestingly, recent studies have documented both at micromolar concentrations in human and cow milk (; ).

Accumulating evidence suggests that NAD+ levels decline with age at a systemic level in diverse organisms, including rodents and humans, contributing to the development of many age-associated pathophysiologies (; ; ).

Therefore, there has been an increasing interest in using NAD+ intermediates as effective interventions to ameliorate or even prevent certain aspects of age-associated functional decline.

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